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Table 3 Other factors associated with bilateral mastectomy during index surgery

From: Preoperative genetic testing impacts surgical decision making in BRCA mutation carriers with breast cancer: a retrospective cohort analysis

  Unilateral or partial mastectomy Bilateral mastectomy p-value
Age
  ≤ 50 (n = 151) 70 (46.4%) 81 (53.6%) <0.05
  > 50 (n = 69) 43 (62.3%) 26 (37.7%) <0.05
Race
 Caucasian (n = 189) 98 (51.9%) 91 (48.1%) NS
 African American (n = 14) 4 (28.6%) 10 (71.4%) NS
 Other (n = 3) 1 (33.3%) 2 (66.7%) NS
 Unknown (n = 14) 10 (71.4%) 4 (28.6%) NS
Laterality
 Unilateral (n = 208) 112 (53.8%) 96 (46.2%) <0.05
 Bilateral (n = 12) 1 (8.3%) 11 (91.7%) <0.05
Histology
 DCIS (n = 24) 13 (54.2%) 11 (45.8%) NS
 IDC (n = 181) 91 (50.3%) 90 (49.7%) NS
 ILC (n = 13) 9 (69.2%) 4 (30.8%) NS
 Other (n = 2) 0 (0.0%) 2 (100%) NS
Grade
 Grade 1 (n = 13) 7 (53.8%) 6 (46.2%) NS
 Grade 2 (n = 58) 29 (50.0%) 29 (50.0%) NS
 Grade 3 (n = 140) 71 (50.7%) 69 (49.3%) NS
 Unknown (n = 9) 6 (66.7%) 3 (33.3%) NS
Triple negative breast cancer
 Yes (n = 80) 34 (42.5%) 46 (57.5%) <0.05
 No (n = 92) 43 (46.7%) 49 (53.3%) NS
 Unknown (n = 48) 36 (75.0%) 12 (25.0%) <0.05
Overall TNM Stage
 In-situ (n = 24) 13 (54.2%) 11 (45.8%) NS
 Stage I (n = 79) 50 (63.3%) 29 (36.7%) <0.05
 Stage II (n = 83) 39 (47.0%) 44 (53.0%) NS
 Stage III (n = 34) 11 (32.4%) 23 (67.6%) <0.05
  1. Percentages within parenthesis represent proportions within their respective rows
  2. NS Not significant